: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism compare proteome
Examples of genome in a Sentence
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Repetitive, non-coding elements are stretches of DNA that repeat many times in the genome and don’t code for proteins themselves, but instead regulate the protein-making machinery inside cells.
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New Atlas, 13 July 2025
Scientific capabilities are soaring, with new tools allowing researchers to examine single cells in precise detail, probe every gene in the genome, and even trace diseases at the molecular level.
—Los Angeles Times, 6 July 2025
The researchers then sequenced the DNA of each fish and searched for areas of the genome and genetic variants that were associated with the growth rate.
—Amber X. Chen, Smithsonian Magazine, 3 July 2025
So, instead of trying to plug all the holes in the mammoth genome, Lamm's company will just edit the main differences of the Asian elephant.
—Katie Grant, Parents, 3 July 2025
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New Atlas, 13 July 2025
Scientific capabilities are soaring, with new tools allowing researchers to examine single cells in precise detail, probe every gene in the genome, and even trace diseases at the molecular level.
—Los Angeles Times, 6 July 2025
The researchers then sequenced the DNA of each fish and searched for areas of the genome and genetic variants that were associated with the growth rate.
—Amber X. Chen, Smithsonian Magazine, 3 July 2025
So, instead of trying to plug all the holes in the mammoth genome, Lamm's company will just edit the main differences of the Asian elephant.
—Katie Grant, Parents, 3 July 2025
See All Example Sentences for genome
Cite this Entry
“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 29 Jul. 2025.
Copy CitationMedical Definition
genome
noun
ge·nome
ˈjē-ˌnōm 
: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. —Lori Oliwenstein, Discover
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