genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

Earlier designs of minimal cells, used to test which components are necessary for lifelike behavior, began with existing living cells and reduced the size of their genomes. — Tara Deans, The Conversation, 8 July 2026

In the new iteration, the project will apply AI tools to scan more than 2 million genomes for more than 500 rare and ultra-rare diseases, Eric Schadt, a computational biologist at the Icahn School of Medicine, told me. — Roxanne Khamsi, The Atlantic, 7 July 2026

This starts with cotton from Texas, which has become more resilient to harsh climate conditions thanks to Avalo’s AI, which is trained on the plant genome. — Roy Stephen Canivel, Footwear News, 7 July 2026

For the new study, scientists examined DNA markers from across the Golden Man’s genome, using statistical methods to fill in gaps where DNA data was damaged or missing. — Mindy Weisberger, CNN Money, 6 July 2026

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb
• centrosome

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover