genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
And perhaps more to the point, the genome might not submit to the kind of straightforward input-output approach that such AI models ultimately assume. Philip Ball, Quanta Magazine, 18 June 2026 The paper treads similar ground as previous research, which has noted large language models’ ability to search genomes for genes that have been sequenced after a patient was first seen in a hospital. Jared Perlo, NBC news, 18 June 2026 The genomes also revealed a unique superantigen, or a microbial toxin that can increase an infection’s severity and activate extreme immune responses — one that appears to have predominantly affected children between the ages of 7 ½ and 11 years old. Ashley Strickland, CNN Money, 17 June 2026 That was partly because the software that assembled the genome from individual fragments of genome sequence was made to treat bacterial sequence as contamination. John Timmer, ArsTechnica, 16 June 2026 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 21 Jun. 2026.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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