follicle

noun

fol·​li·​cle ˈfä-li-kəl 

1

a

: a small anatomical cavity or deep narrow-mouthed depression

b

: a small lymph node

c

: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells

especially : graafian follicle

2

: a dry dehiscent one-celled many-seeded fruit (as of the milkweed) that has a single carpel and opens along one suture

follicular

fə-ˈli-kyə-lər 

fä-

adjective

Examples of follicle in a Sentence

Recent Examples on the Web

It’ll eventually be pushed out by a new follicle underneath in the telogen phase, and the process repeats itself. —Alanna Martine Kilkeary, Glamour, 17 June 2026

Regardless of age, a poor response to ovarian stimulation—for example, a low estrogen level or a low number of follicles developing—indicates that the treatment is not going well, Klipstein says. —Heather Grossmann, Parents, 16 June 2026

Androgens — which women also produce — can then cause follicle miniaturization, similar to what is observed in male androgenetic alopecia. —Ascend Agency, New York Daily News, 16 June 2026

The Kérastase Chronologiste Revitalizing Youth Shampoo removes buildup, cleanses the scalp, softens and strengthens strands (meaning less breakage), increases moisture starting at the root, improves follicle health (meaning less shedding), and imparts shine. —Tamim Alnuweiri, InStyle, 15 June 2026

Word History

Etymology

New Latin folliculus, from Latin, diminutive of follis bag — more at fool

First Known Use

1715, in the meaning defined at sense 1a

Phrases Containing follicle

• follicle mite
• follicle-stimulating hormone
• Graafian follicle
• hair follicle

Rhymes for follicle

• diabolical
• symbolical

Kids Definition

follicle

noun

fol·​li·​cle ˈfäl-i-kəl 

1

a

: a small cavity or a deep bodily depression with a narrow mouth (as one from which a hair grows)

b

: graafian follicle

2

: a dry one-celled fruit (as in the milkweed) that splits open by one seam when ripe

follicular

fə-ˈlik-yə-lər 

fä-

adjective

Medical Definition

follicle

noun

fol·​li·​cle ˈfäl-i-kəl 

1

: a small anatomical cavity or deep narrow-mouthed depression

especially : a small simple or slightly branched gland : crypt

2

: a small lymph node

3

: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells : ovarian follicle

especially : graafian follicle

follicular

fə-ˈlik-yə-lər, fä- 

adjective