fibroblast

noun

fi·​bro·​blast ˈfī-brə-ˌblast  ˈfi- 

: a connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms

fibroblastic

ˌfī-brə-ˈbla-stik  ˌfi- 

adjective

Examples of fibroblast in a Sentence

Recent Examples on the Web

Certain peptides signal fibroblasts to ramp up collagen and elastin production, while others reinforce the skin barrier or calm inflammation. —Adam Hurly, Robb Report, 28 Aug. 2025

By reprogramming ordinary cells—like skin fibroblasts—into stem cells, scientists hope to create eggs and sperm from individuals long gone. —Tony Bradley, Forbes.com, 22 Aug. 2025

Of these, seven showed clear anti-aging effects when tested directly on aged human fibroblasts (cells that form connective tissue) and keratinocytes (the major cell type of the outermost layers of the skin) in the lab. —New Atlas, 10 Aug. 2025

The process recruits fibroblasts, the cells that lay down scar tissue. —Alison Escalante, Forbes, 27 Feb. 2025

Word History

Etymology

International Scientific Vocabulary

First Known Use

1876, in the meaning defined above

Phrases Containing fibroblast

• fibroblast growth factor

Rhymes for fibroblast

• oblast

Medical Definition

fibroblast

noun

fi·​bro·​blast

ˈfīb-rə-ˌblast also ˈfib-

: a connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms

fibroblastic

ˌfīb-rə-ˈblas-tik  ˌfib- 

adjective