fentanyl

noun

fen·​ta·​nyl ˈfen-tə-ˌnil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
During 2023, in San Diego County, 1,203 people died from an accidental overdose of fentanyl. Elizabeth Marie Himchak, San Diego Union-Tribune, 5 Aug. 2025 The documentary will also delve into the law enforcement and criminal investigation side of things, revealing how special agents brought dealers to justice after selling lethal doses of fentanyl to users. Michael Saponara, Billboard, 4 Aug. 2025 The number of pounds of fentanyl dropped by that percentage between May and June during seizure operations by the California National Guard’s Counterdrug Task Force, the Governor’s Office said in a news release. Dave Mason, The Washington Examiner, 2 Aug. 2025 Canada faces a 35% tariff The U.S.’s northern neighbor got a higher rate because Trump is dissatisfied with Canada’s efforts to stop the flow of fentanyl. Diane Brady, Fortune, 1 Aug. 2025 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 21 Aug. 2025.

Medical Definition

fentanyl

noun
fen·​ta·​nyl ˈfent-ᵊn-ˌil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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