exon

noun

ex·​on ˈek-ˌsän How to pronounce exon (audio)
: a polynucleotide sequence in a nucleic acid that codes information for protein synthesis and that is copied and spliced together with other such sequences to form messenger RNA compare intron
exonic adjective

Examples of exon in a Sentence

Recent Examples on the Web
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The researchers focused on a genetic element known as a poison exon. Jenny Lehmann, Discover Magazine, 18 Mar. 2025 Most of the time, cells connect exons from the same pre-RNA molecule to make the mRNA. Bymitch Leslie, science.org, 24 Oct. 2024 Exondys 51 is used to treat the 13 percent of patients with disease caused by an error in the DNA sequence known as exon 51. BostonGlobe.com, 14 Dec. 2019 Exondys 51 is used to treat the 13% of patients with disease caused by an error in the DNA sequence known as exon 51. Damian Garde, STAT, 12 Dec. 2019 In one case, at Stanford, a toddler was diagnosed with two rare diseases, including a connective tissue disorder called Marfan Syndrome, after doctors conducted a form of sequencing that looks for changes in coded genetic segments known as exons. Anna Gorman, CNN, 8 May 2017

Word History

Etymology

expressed sequence + -on entry 2

First Known Use

circa 1978, in the meaning defined above

Time Traveler
The first known use of exon was circa 1978

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Cite this Entry

“Exon.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/exon. Accessed 9 Sep. 2025.

Medical Definition

exon

noun
ex·​on ˈek-ˌsän How to pronounce exon (audio)
: a polynucleotide sequence in a nucleic acid that codes information for protein synthesis and that is copied and spliced together with other such sequences to form messenger RNA compare intron
exonic adjective

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