View your list of saved words. (You can log in using Facebook.)
About Our Definitions: All forms of a word (noun, verb, etc.) are now displayed on one page.
Definition of DIABETES INSIPIDUS
: a disorder of the pituitary gland characterized by intense thirst and by the excretion of large amounts of urine
Origin of DIABETES INSIPIDUS
New Latin, literally, bland diabetes
First Known Use: circa 1846
Medical Definition of DIABETES INSIPIDUS
: a disorder that is caused by insufficient secretion of vasopressin by the pituitary gland or by a failure of the kidneys to respond to circulating vasopressin and that is characterized by intense thirst and by the excretion of large amounts of urine—see central diabetes insipidus, nephrogenic diabetes insipidus
Endocrine disorder causing extreme thirst and excessive production of very dilute urine, apparently due to lack of antidiuretic hormone (vasopressin, which regulates the kidney's water conservation and urine production) or failure of the kidney tubules to respond to it. Injections of synthetic vasopressin are effective if the hormone is lacking but not if the response is absent. Disorders of the hypothalamus are one cause of diabetes insipidus.