Simple Definition of despise
: to dislike (something or someone) very much
Examples of despise
She was despised as a hypocrite.
<I despise anchovies on pizza, and I refuse to eat them!>
Origin of despise
Middle English, from Anglo-French despis-, stem of despire, from Latin despicere, from de- + specere to look — more at spy
First Known Use: 14th century
Synonym Discussion of despise
Seen and Heard
What made you want to look up despise? Please tell us where you read or heard it (including the quote, if possible).