Simple Definition of depopulate
: to greatly reduce the number of people living in (a city, region, etc.)
Examples of depopulate in a sentence
Large areas of the country had been depopulated by disease.
Origin and Etymology of depopulate
Latin depopulatus, past participle of depopulari, from de- + populari to ravage
First Known Use: 1548
Learn More about depopulate
Britannica English: Translation of depopulate for Arabic speakers
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