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cyclooxygenase

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noun cy·clo·ox·y·gen·ase \-ˈäk-si-jə-ˌnās\

Definition of cyclooxygenase

  1. :  an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins and that has two isoforms of which one is involved in the creation of prostaglandins which mediate inflammation and pain



Origin and Etymology of cyclooxygenase

cycl- + oxygenase, an enzyme, from oxygen + -ase


First Known Use: 1975


Medical Dictionary

cyclooxygenase

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noun cy·clo·ox·y·gen·ase \ˌsī-klō-ˈäk-si-jə-ˌnās, -äk-ˈsij-ə-, -ˌnāz\

Medical Definition of cyclooxygenase

  1. :  an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins, that is inactivated by aspirin and other NSAIDs, and that has two isoforms of which one is involved in the cascade of events producing the pain and inflammation of arthritis and the other is not—see cox-1, cox-2




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