Creutzfeldt-Jakob disease


Creutz·feldt–Ja·kob disease

noun \ˈkrits-ˌfelt-ˈyä-(ˌ)kōb-\

medical : a disease of the brain that causes people to lose their memory, to no longer be able to control their muscles, and eventually to die

Full Definition of CREUTZFELDT-JAKOB DISEASE

:  a rare progressive fatal encephalopathy caused by a prion and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination

Variants of CREUTZFELDT-JAKOB DISEASE

Creutz·feldt–Ja·kob disease also Creutz·feld–Ja·kob disease \ˈkrits-ˌfelt-ˈyä-(ˌ)kōb-\

Origin of CREUTZFELDT-JAKOB DISEASE

Hans G. Creutzfeldt †1964 German psychiatrist and Alfons M. Jakob †1931 German psychiatrist
First Known Use: 1963

Creutz·feldt–Ja·kob disease

noun    (Medical Dictionary)

Medical Definition of CREUTZFELDT–JAKOB DISEASE

: a rare progressive fatal prion disease marked by the development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination—abbreviation CJD; called also Jakob-Creutzfeldt disease; see variant creutzfeldt-jakob disease

Biographical Note for CREUTZFELDT–JAKOB DISEASE

Creutz·feldt \ˈkroits-ˌfelt\ Hans Gerhard (1885–1964), and Ja·kob \ˈyä-ˌkōp\ Alfons Maria (1884–1931), German psychiatrists. Creutzfeldt published his description of the disease now known as Creutzfeldt-Jakob disease in 1920. A year later in the same neurological journal Jakob offered his description. Although Creutzfeldt's description is the original one, Jakob's is the better known of the two, so the disease is named in honor of both men.

Variants of CREUTZFELDT–JAKOB DISEASE

Creutz·feldt–Ja·kob disease also Creutz·feld–Ja·kob disease \ˌkrits-ˌfelt-ˌyä-(ˌ)kōb-\

Creutzfeldt-Jakob disease

noun    (Concise Encyclopedia)

Rare fatal disease of the central nervous system. It destroys brain tissue, making it spongy and causing progressive loss of mental functioning and motor control. The disease commonly arises in adults between the ages of 40 and 70. Patients usually die within a year. There is no known cure. The disease is caused by a prion that builds up in neurons. Inherited or random mutation accounts for 99% of cases; the rest come from prion exposure during medical procedures and possibly from eating the meat of cattle with mad cow disease.

Variants of CREUTZFELDT-JAKOB DISEASE

Creutzfeldt-Jakob disease or CJD

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