Definition of COX–2 inhibitor
: any of a class of drugs used to treat the pain and inflammation of arthritis by selectively blocking the variant of cyclooxygenase causing these symptoms
First Known Use of cox–2 inhibitor
Medical Definition of COX–2 inhibitor
: any of a class of drugs (as celecoxib) that selectively block the isoform COX-2 but not the isoform COX-1 of cyclooxygenase and that are intended to relieve the pain and inflammation of arthritis while minimizing gastrointestinal side effects—called also COX-2 blocker
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