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Definition of COX-2 INHIBITOR
: any of a class of drugs used to treat the pain and inflammation of arthritis by selectively blocking the variant of cyclooxygenase causing these symptoms
First Known Use of COX-2 INHIBITOR
Medical Definition of COX–2 INHIBITOR
: any of a class of drugs (as celecoxib) that selectively block the isoform COX-2 but not the isoform COX-1 of cyclooxygenase and that are intended to relieve the pain and inflammation of arthritis while minimizing gastrointestinal side effects—called also COX-2 blocker