collagenase

noun

col·​la·​ge·​nase kə-ˈla-jə-ˌnās How to pronounce collagenase (audio)
ˈkä-lə-jə-,
-ˌnāz How to pronounce collagenase (audio)
: any of a group of proteolytic enzymes that decompose collagen and gelatin

Examples of collagenase in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The overactivity of the skin enzyme collagenase can degrade collagen, which is a major factor in the loss of skin elasticity and thickness and contributes to skin aging and the formation of wrinkles. New Atlas, 6 Sep. 2024 Retinoids block the production of collagenase and turn on the genes that make your skin produce collagen. Dr. Leslie Baumann, miamiherald, 27 Apr. 2018

Word History

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of collagenase was in 1926

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Cite this Entry

“Collagenase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/collagenase. Accessed 11 Sep. 2025.

Medical Definition

collagenase

noun
col·​la·​ge·​nase kə-ˈlaj-ə-ˌnās How to pronounce collagenase (audio) ˈkäl-ə-jə- How to pronounce collagenase (audio)
-ˌnāz
: any of a group of proteolytic enzymes that decompose collagen and gelatin

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