clinical

adjective

clin·​i·​cal ˈkli-ni-kəl 

1

: of, relating to, or conducted in or as if in a clinic: such as

a

: involving direct observation of the patient

clinical diagnosis

b

: based on or characterized by observable and diagnosable symptoms

clinical treatment

clinical tuberculosis

2

: analytical or coolly dispassionate

describing the situation with clinical detachment

3

US, informal : done or performed with excellence and precision : exemplary

In the meantime Bryant … continued his clinical shooting, which has allowed him to more than double his scoring average …

—Alexander Wolff

clinically

ˈkli-ni-k(ə-)lē 

adverb

Examples of clinical in a Sentence

Both experimental and clinical evidence show that the treatment is effective.

She enjoys her clinical practice but is looking forward to working in a laboratory.

Three hundred patients were involved in the clinical study.

Recent Examples on the Web

Because pain is so subjective—and because of the difficulty in substantiating conditions such as whiplash and soft-tissue damage—surgery had the benefit not just of running up the clinical expense of an accident but also of seeming to ratify its legitimacy. —Patrick Radden Keefe, New Yorker, 13 Apr. 2026

At Gilead, where more than 50 clinical programs are active across phases one through three, that kind of attrition is a constant feature of the work. —Ruth Umoh, Fortune, 13 Apr. 2026

The therapy is also part of clinical guidelines to prevent and treat oral mucositis — painful mouth ulcers and inflammation that are common among patients undergoing treatments such as chemotherapy and radiation. —Maria Godoy, NPR, 13 Apr. 2026

Here is where the hurdle transcends clinical diagnostics. —Lucy Jones april 11, Miami Herald, 11 Apr. 2026

Word History

First Known Use

circa 1728, in the meaning defined at sense 1

Phrases Containing clinical

• clinical depression
• clinical psychologist
• clinical psychology
• clinical thermometer
• clinical trial

Rhymes for clinical

• binnacle
• cynical
• pinnacle
• nonclinical
• preclinical
• rabbinical
• subclinical

Kids Definition

clinical

adjective

clin·​i·​cal ˈklin-i-kəl 

1

: of, relating to, or conducted in or as if in a clinic

clinical examination

2

: involving or based on direct observation of the patient

clinical studies

clinically

-i-k(ə-)lē 

adverb

Medical Definition

clinical

adjective

clin·​i·​cal ˈklin-i-kəl 

: of, relating to, or conducted in or as if in a clinic: as

a

: involving or concerned with the direct observation and treatment of living patients

engaged in full-time clinical practice

clinical professor of obstetrics and gynecology

b

: of, relating to, based on, or characterized by observable and diagnosable symptoms of disease

the clinical picture on admission was that of mild depression in an extremely rigid personality

—Occupational Therapy & Rehabilitation

three of these six foods were actually the cause of symptoms, and upon their elimination, clinical cure was effected

—Journal of Pediatrics

clinically

-k(ə-)lē 

adverb

a clinically significant infection

clinically effective therapies