Dictionary

Cayuse

noun Cay·use \ˈkī-ˌyüs, kī-ˈ\
plural Cayuse or Cayuses

Definition of CAYUSE

1
:  a member of an American Indian people of Oregon and Washington
2
plural cayuses not capitalized West :  a native range horse
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Origin of CAYUSE

origin unknown
First Known Use: 1825

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