blot

¹blot

noun \ˈblät\

Definition of BLOT

1

: a soiling or disfiguring mark : spot

2

: a mark of reproach : moral flaw

3

: a usually nitrocellulose or nylon sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and is used to identify specific components of the spots by applying a molecular probe (as a complementary nucleic acid or a radio labeled antibody) — compare southern blot, western blot

Origin of BLOT

Middle English

First Known Use: 14th century

Rhymes with BLOT

aught, baht, bot, clot, cot, dot, ghat, grot, hot, jot, khat, knot, kyat, lot, lotte, Mott, motte, naught, not, plot, pot, rot, scot, Scot, shot, skat, slot, snot, sot, spot, squat, stot, swat, swot, tot, trot, watt, Watt, what, wot, yacht

²blot

verb

blot·ted blot·ting

Definition of BLOT

transitive verb

1

: to spot, stain, or spatter with a discoloring substance

2

obsolete : mar; especially : to stain with infamy

3

a : to dry (as writing) with an absorbing agent

b : to remove with absorbing material <blotting up spilled water>

intransitive verb

1

: to make a blot

2

: to become marked with a blot

Examples of BLOT

1. Don't rub the wine stain. Blot it dry with a paper towel.
2. Blot your lipstick with a tissue.

First Known Use of BLOT

15th century

³blot

noun

Definition of BLOT

1

: a lone backgammon man exposed to capture

2

archaic : a weak or exposed point

Origin of BLOT

perhaps from Dutch bloot naked, exposed, from Middle Dutch; akin to Middle High German bloz bare

First Known Use: 1595

blot

noun \ˈblät\   (Medical Dictionary)

Medical Definition of BLOT

: a nitrocellulose sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and that is used to identify specific components of the spots by applying a suitable molecular probe (as a complementary nucleic acid or a radiolabeled antibody)—see northern blot, southern blot, western blot

—blot transitive verb