: any of numerous compounds characterized by a 5-membered ring containing at least one nitrogen atom

Examples of azole in a Sentence

Recent Examples on the Web Brexafemme is priced at a substantial premium compared to older azole treatment options, such as fluconazole. Joshua Cohen, Forbes, 6 July 2022 Just under half of the samples collected were resistant to at least one azole drug and over 10% of the samples were resistant to two or more azoles. Victoria Forster, Forbes, 25 Apr. 2022 In the Texas outbreak, in addition to the two pan-resistant cases, there were five patients with C. auris that was resistant to both echinocandins and fluconazole, an antifungal drug in the azole class. Helen Branswell, STAT, 22 July 2021 Initially, Brexafemme’s target sub-population will likely be women with azole-resistant infections or those who don’t respond to or can’t tolerate existing drugs. Joshua Cohen, Forbes, 7 June 2021 But, antifungal resistance has become a problem for some diagnosed with a vaginal yeast infection and using azole antifungals. Joshua Cohen, Forbes, 7 June 2021 And there are other problems: Only one class of drugs, the azoles, can be taken orally. Kai Kupferschmidt, Science | AAAS, 22 Oct. 2019 More than 90 percent were resistant to azoles; 30 percent were resistant to the class that contains amphotericin; and globally, up to 20 percent were resistant to the last-ditch echinocandins. Maryn McKenna, WIRED, 13 July 2018 This novel yeast was already showing some resistance to the first-choice antifungals that would have been used against it, a family of compounds called azoles that can be given by mouth. Maryn McKenna, WIRED, 13 July 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'azole.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

circa 1899, in the meaning defined above

Time Traveler
The first known use of azole was circa 1899

Dictionary Entries Near azole

Cite this Entry

“Azole.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/azole. Accessed 19 Mar. 2024.

Medical Definition

: any of numerous compounds characterized by a 5-membered ring containing at least one atom of nitrogen
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