Quantcast
Merriam-Webster Logo
  • Dictionary
  • Thesaurus
  • Scrabble
  • Spanish Central
  • Learner's Dictionary

ataxia–telangiectasia

play
noun atax·ia–tel·an·gi·ec·ta·sia \-ˌte-ˌlan-jē-ˌek-ˈtā-zh(ē-)ə, -tē-, -tə-\

Definition of ataxia–telangiectasia

  1. :  an inherited systemic disorder marked especially by progressive pathological changes in the nervous system resulting in loss of motor coordination and by increased susceptibility to cancer especially of lymphoid tissue



1961

First Known Use of ataxia–telangiectasia

1961


Medical Dictionary

ataxia–telangiectasia

noun atax·ia–tel·an·gi·ec·ta·sia

Medical Definition of ataxia–telangiectasia

  1. :  an inherited, systemic disorder that is marked especially by progressive pathological changes in the nervous system resulting in loss of motor coordination, telangiectasias especially on the eyes, ears, and cheeks, and immunodeficiency leading to increased susceptibility to cancer especially of lymphoid tissue <Many children with ataxia-telangiectasia die from respiratory failure or cancer by their teens or early 20s.—Bill Minutaglio, The Dallas Morning News, 22 Dec. 1994> <Defects in such a multifunctional protein might explain many of the clinical manifestations seen in patients with ataxia–telangiectasia.—Michael Kastan, The New England Journal of Medicine, 7 Sept. 1995> Ataxia-telangiectasia is inherited as a recessive autosomal trait requiring that both parents pass on a copy of the defective gene on a chromosome other than a sex chromosome.




Seen and Heard

What made you want to look up ataxia–telangiectasia? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

the lowest point

Get Word of the Day daily email!

WORD GAMES

Take a 3-minute break and test your skills!

fox-in-summer-forest

Which of these is a synonym of inchoate?

formless massive frightening experimental
Name That Thing

Test your visual vocabulary with our 10-question challenge!

TAKE THE QUIZ
SCRABBLE® Sprint

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ