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anti–idiotype

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noun an·ti–id·io·type \ˌan-tē-ˈi-dē-ə-ˌtīp, ˌan-tī-\

Definition of anti–idiotype

  1. :  an antibody that binds to the antigen-combining site of another antibody either suppressing or enhancing the immune response

anti–idiotypicplay \-ˌi-dē-ə-ˈti-pik\ adjective


1973

First Known Use of anti–idiotype

1973


Medical Dictionary

anti–idiotype

noun an·ti–id·io·type \ˌan-tī-ˈid-ē-ə-ˌtīp\

Medical Definition of anti–idiotype

  1. :  an antibody that binds to the antigen combining site of another antibody either suppressing or enhancing the immune response <Anti-idiotypes are secondary antibodies manufactured by the immune system in reaction to the presence of antibodies, the body's basic germ fighters.—Craig D. Rose, The San Diego Union-Tribune, 11 Mar. 1988>

anti–idiotype or anti–idiotypic \-ˌid-ē-ə-ˈtip-ik\ play adjective <Recent studies … indicate, however, that other cancer cells expressing a different idiotype can emerge during anti-idiotype treatment.—Ronald C. Kennedy et al., Scientific American, July 1986> <Anti-idiotypic antibodies that bind to the idiotype marker (antigen-binding site) on B cells, may also suppress autoantibody production.—Jacqueline Parkin and Bryony Cohen, The Lancet, 2 June 2001>



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