Dictionary

antagonist

noun an·tag·o·nist \an-ˈta-gə-nist\

: a person who opposes another person

Full Definition of ANTAGONIST

1
:  one that contends with or opposes another :  adversary, opponent
2
:  an agent of physiological antagonism: as
a :  a muscle that contracts with and limits the action of an agonist with which it is paired —called also antagonistic muscle
b :  a chemical that acts within the body to reduce the physiological activity of another chemical substance (as an opiate); especially :  one that opposes the action on the nervous system of a drug or a substance occurring naturally in the body by combining with and blocking its nervous receptor — compare agonist 2b

Examples of ANTAGONIST

  1. <please name the novel's hero and his antagonist>
  2. <his antagonist in the boxing match>
  3. They are interested in character first, and in Don, a foul-mouthed psychopath with a hair-trigger temper and buried longings for Gal's wife, they have created a truly scary antagonist. —David Ansen, Newsweek, 18 June 2001

Origin of ANTAGONIST

(see antagonize)
First Known Use: 1575

antagonist

noun an·tag·o·nist \-nəst\   (Medical Dictionary)

Medical Definition of ANTAGONIST

:  an agent that acts in physiological opposition <contact between a tooth and its antagonist in the opposing jaw>: as a :  a muscle that contracts with and limits the action of an agonist with which it is paired—called also antagonistic muscle; compare agonist 1, synergist 2 b :  a chemical that acts within the body to reduce the physiological activity of another chemical substance (as an opiate); especially :  one that opposes the action on the nervous system of a drug or a substance occurring naturally in the body by combining with and blocking its nervous receptor—compare agonist 2

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