anneal


an·neal

verb \ə-ˈnēl\

: to heat and then slowly cool (metal, glass, etc.) in order to make it stronger

Full Definition of ANNEAL

transitive verb
1
a :  to heat and then cool (as steel or glass) usually for softening and making less brittle; also :  to cool slowly usually in a furnace
b :  to heat and then cool (double-stranded nucleic acid) in order to separate strands and induce combination at lower temperature with complementary strands
intransitive verb
:  to be capable of combining with complementary nucleic acid by a process of heating and cooling

Origin of ANNEAL

Middle English anelen to set on fire, from Old English onǣlan, from on + ǣlan to set on fire, burn, from āl fire; akin to Old English ǣled fire, Old Norse eldr
First Known Use: 1664

an·neal

transitive verb \ə-ˈnē(ə)l\   (Medical Dictionary)

Medical Definition of ANNEAL

1
: to heat and then cool (as steel or glass) usually for softening and making less brittle
2
: to heat and then cool (double-stranded nucleic acid) in order to separate strands and induce combination at lower temperatures especially with complementary strands
intransitive verb
: to be capable of combining with complementary nucleic acid by a process of heating and cooling <some bacterial nucleic acid anneals well with eukaryotic DNA>

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