Simple Definition of anneal
: to heat and then slowly cool (metal, glass, etc.) in order to make it stronger
Full Definition of anneal
1 a : to heat and then cool (as steel or glass) usually for softening and making less brittle; also : to cool slowly usually in a furnace b : to heat and then cool (double-stranded nucleic acid) in order to separate strands and induce combination at lower temperature with complementary strands
: to be capable of combining with complementary nucleic acid by a process of heating and cooling
Did You Know?
If you were looking for a saying to apply to the word anneal, it might be "everything old is new again." The word was originally associated with one of the oldest technologies of humankind: fire. It derives from the Old English word onælan, which was formed from the Old English root āl, meaning "fire." In its earliest known uses, which date from around the year 1000, anneal meant simply "to set on fire." That sense has become obsolete, however, and nowadays anneal is associated with a much more recent technological development. It has come to be used in the context of DNA research, in reference to the heating and cooling of double-stranded nucleic acid.
Origin and Etymology of anneal
Middle English anelen to set on fire, from Old English onǣlan, from on + ǣlan to set on fire, burn, from āl fire; akin to Old English ǣled fire, Old Norse eldr
First Known Use: 1664
Rhymes with anneal
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ANNEAL Defined for Kids
Definition of anneal for Students
: to heat (as glass or steel) and then cool so as to toughen and make less brittle
Medical Definition of anneal
1: to heat and then cool (as steel or glass) usually for softening and making less brittle
2: to heat and then cool (double-stranded nucleic acid) in order to separate strands and induce combination at lower temperatures especially with complementary strands
intransitive verb: to be capable of combining with complementary nucleic acid by a process of heating and cooling <some bacterial nucleic acid anneals well with eukaryotic DNA>
Seen and Heard
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