aminopterin

noun

am·​i·​nop·​ter·​in ˌa-mə-ˈnäp-tə-rən 

: a derivative C₁₉H₂₀N₈O₅ of glutamic acid that is a folic acid antagonist and has been used as a rodenticide and antileukemic agent

Examples of aminopterin in a Sentence

Recent Examples on the Web

In the late 1940s, legendary cancer researcher Sydney Farber and colleagues reported successfully treating acute leukemia in children with a new drug called aminopterin. — Gwen Nichols, STAT, 30 Dec. 2019

In 1947 aminopterin, a chemical which messes up cell division by interrupting the metabolism of folic acid, was found to produce remissions in children with acute leukaemia. — The Economist, 14 Sep. 2017

Word History

Etymology

amino + pteroylglutamic acid + -in

First Known Use

1948, in the meaning defined above

Medical Definition

aminopterin

noun

am·​i·​nop·​ter·​in ˌam-ə-ˈnäp-tə-rən 

: a derivative C₁₉H₂₀N₈O₅ of glutamic acid that is a folate antagonist and has been used as a rodenticide and antileukemic agent