Agnew play biographical name Ag·new \ˈag-ˌnü, -ˌnyü\ Definition of Agnew Spi*ro play \ˈspir-(ˌ)ō\ Theodore 1918–1996 Am. polit.; vice pres. of the United States (1969–73) Writing? Check your grammar now! Seen and Heard What made you want to look up Agnew? Please tell us where you read or heard it (including the quote, if possible).