zymogen


zymogen

Any of a class of proteins that are secreted by cells and are inactive precursors of enzymes. Transformation into active enzymes occurs as one or more peptide bonds in the zymogen are cleaved. Examples include trypsinogen and chymotrypsinogen, secreted by the pancreas and converted by proteolysis in the small intestine into the active enzymes trypsin and chymotrypsin; and numerous coagulation factors.

Variants of ZYMOGEN

zymogen or proenzyme

This entry comes from Encyclopædia Britannica Concise.
For the full entry on zymogen, visit Britannica.com.

Seen & Heard

What made you look up zymogen? Please tell us what you were reading, watching or discussing that led you here.