Powerful enzyme in gastric juice (see stomach) that partially digests proteins in food. Glands in the stomach lining make pepsinogen, a zymogen (enzyme precursor) converted to pepsin by the hydrochloric acid in gastric juice. Pepsin is active only in the acid environment of the stomach (pH 1.5–2.5 or less); it is ineffective in the intestine (pH 7, neutral). It is used commercially in some cheese making, in the leather industry to remove hair and residual tissue from hides, and in the recovery of silver from discarded photographic films by digesting the gelatin layer that holds the silver.

This entry comes from Encyclopædia Britannica Concise.
For the full entry on pepsin, visit

Seen & Heard

What made you look up pepsin? Please tell us what you were reading, watching or discussing that led you here.

Get Our Free Apps
Voice Search, Favorites,
Word of the Day, and More
Join Us on FB & Twitter
Get the Word of the Day and More