Issus, Battle of
(333 BC) Battle on the Issus plain near the Gulf of Iskenderun (in present-day southern Turkey) in which Alexander the Great, on the offensive, defeated Darius III, last king of the Achaemenian dynasty. The Macedonians were said to have lost only 450 men. Darius escaped, but the victory led to Alexander's victories over Phoenicia and Egypt.
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