View your list of saved words. (You can log in using Facebook.)
Relatively rare, hereditary neurological disease that is characterized by irregular and involuntary movements of the muscles. Huntington chorea is caused by a genetic mutation that causes degeneration of neurons in a part of the brain that controls movement. Symptoms usually appear between ages 35 and 50. They begin with occasional jerking or writhing movements, which are absent during sleep, and progress to random, uncontrollable, and often violent twitchings and jerks. Symptoms of mental deterioration begin later and include memory loss, dementia, bipolar disorder, or schizophrenia. There is no effective therapy or cure, and the disease invariably proves fatal. A child of a person with Huntington chorea has a 50% chance of developing the disease.
This entry comes from Encyclopædia Britannica Concise. For the full entry on Huntington chorea, visit Britannica.com.
Seen & Heard
What made you look up Huntington chorea? Please tell us what you were reading, watching or discussing that led you here.