Common name of acetylsalicylic acid, an organic compound introduced in 1899. The ester of salicylic acid and acetic acid, it inhibits production of prostaglandins in the body. Its analgesic, fever-reducing, and anti-inflammatory effects make it useful in treating headaches, muscle and joint aches, arthritis pain, and the symptoms of mild fevers and infections. It also has anticoagulant activity and is taken in low doses by coronary heart disease patients to prevent heart attack. Prolonged use may cause stomach bleeding and peptic ulcer, and its use in children with fever has been linked to Reye syndrome. See also acetaminophen; ibuprofen; NSAID.
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